Curriculum Vitae of Carl M. Anderson
Assistant Psychobiologist in the Brain Imaging Center, McLean Hospital & Assistant Professor of Psychiatry, Harvard Medical School
carl_anderson@hms.harvard.edu
Publications:
Online Abstracts and Posters:
last update 03-08-06
Professional Address:
Developmental Biopsychiatry Research Program &
Dept. Psychiatry, Harvard Medical School.
McLean Hospital 115 Mill St. Belmont, MA 02178
Ph: 617-855-2972
Fax: 617-855-3712
Email: carl_anderson@hms.harvard.edu
Education:
1983 B.S. (Microbiology) University of Florida, Gainesville, FL
1992 M.A. (Experimental Psychology) Duke University, Durham, NC
1995 Ph.D. (Developmental Psychobiology & Complex Systems)
Florida Atlantic University, Boca Raton, FL
Academic Appointments:
1998- Instructor in Psychiatry, Harvard Medical School
Awards and Honors:
1992-1994 National Institute of Mental Health Fellowship, Center for Complex Systems, Florida Atlantic University
1994 The Bryant W. Robinson Neurological Foundation Award
1995 The Newell Fellowship
1996 Dissertation Award, International Society for Developmental Psychobiology
1999 Young Investigator Award, 39th Annual NCDEU meeting
Memberships:
1982- American Association for the Advancement of Science
1989- Society for Neuroscience
1996- International Society for Developmental Psychobiology
2000-The Society of Biological Psychiatry
REPORT OF RESEARCH (top)
Major Research Interests:
Functional Magnetic Resonance Imaging of the Cerebellar Vermis
Developmental Psychobiology (functions of fetal REM sleep)
Diagnosis and Treatment of ADHD, Autism, Child Abuse, Dyslexia, PTSD and Drug Addiction
Fractals, Complex Systems and Neurobiology
Neurobiology of the Limbic System and Emotion
Consciousness and the Dual Mind
Narrative Description of Research
I began my scientific career as a research technician in 1984, under Dr. Clinton D. Kilts, then the director of the Psychopharmacology Laboratory in the Psychiatry department at Duke University Medical Center (DUMC). Although my initial work involved performing gas chromatographic analyses of tricyclic antidepressants in patients' blood samples, I quickly moved on to basic research in the neuropharmacology of antipsychotic drugs. Over the next eight years, under the guidance of Dr. Kilts, I participated in fundamental work that included studies of the effects of chronic antipsychotic drug administration on catecholamine systems and the distribution and neuropharmacology of release regulating mesoamygdaloid dopamine autoreceptors. I spend a great deal of time in the DUMC library during those years, reading up on the anatomy and physiology of the amygdala, monoamines and neuropeptides. My study of the amygdala, lead me to learn about the olfactory system, around which I was synthesizing a personal conceptual model of brain function. I started reading the pioneering works of Walter Freeman such as his book, Mass Action in the Nervous System, which was an attempt to model the olfactory system. During this time, I was encouraged by Dr. Warren G. Hall, a leading researcher in development of olfactory learning, to enter the graduate program in experimental psychology at Duke University. There I obtained a master's degree, using the innovative application of HPLC and behavioral neuropharmacological techniques developed with Dr. Kilts, in order to investigate developmentally, noradrenergic modulation of olfactory orienting in rats.
As a graduate student interested in dynamic brain function, I came under the influence of the pioneering work of Dr. Arnold Mandell on the application of nonlinear dynamics to psychopharmacology. At the same time, I had become disenchanted with the traditional methods of assessment of neurotransmitter concentrations as a post-morbid "window" into brain dynamics. These factors led me to begin a new course of graduate studies in nonlinear dynamics in the Center for Complex Systems at Florida Atlantic University where my career emphasis shifted to the developmental study of brain dynamics. With Dr. Mandell, I investigated the role of rapid eye movement (REM) sleep in fetal and neonatal brain development. We observed that periods of nuchal atonia, i.e., loss of neck muscle tone, occurring with REM sleep were organized in a self-similar pattern of phasic bursts of EMG (see appendix IV). My work with Dr. Mandell instilled in me a novel view of brain organization based on the properties of fractal processes in time (described in a chapter published in the book "Fractals of the Brain: Fractals of the Mind".
My interest in ibogaine started while I was completing my disseration. At this time, Dr. Mandell was invited by Dr. Deborah C. Mash to present a guest lecture on nonlinear dynamics at the University of Miami medical school. Dr. Mandell invited me to accompany him, and I met and talked with Dr. Mash and her post-doc, Julie Staley, at lunch. Dr. Staley informed me that ibogaine induced intense REM sleep episodes during its therapeutic action in drug addicts. I knew that delirium tremens was thought to be a REM-rebound-like process, and was intrigued by the possibility that my dissertation work might have implications for conceptualizing ibogaine's mechanism of action. I then completed a comprehensive literature review of the basic neurobiology and clinical psychopharmacology of ibogaine which lead me to propose a mechanism of action for this drug, based impart on my dissertation, and then incorporated it into a theoretical paper entitled: Ibogaine therapy in chemical dependency and post-traumatic stress disorder: A hypothesis involving the fractal nature of fetal REM sleep and interhemispheric reintegration, published in Multidisciplinary Association for Psychedelic Studies (MAPS) newsletter in 1998.
In 1995, with Dr. Mandell's help I secured a postdoctoral position at McLean Hospital, in the Developmental Biopsychiatry Research Program, headed by Dr. Marty Teicher, with the intention of applying the knowledge I had acquired in psychopharmacology, developmental neurobiology, and dynamical systems to the diagnosis and treatment of clinical disorders such as childhood ADHD and the enduring effects of early child abuse. Early in my career at Mclean, I came under the influence and guidance of Dr. Perry Renshaw, Director of the Brain Imaging Center. At that time, I knew very little of MRI or of fMRI methods Dr. Teicher and I were using in our studies. Dr. Renshaw, with great patience and after a number of impromptu lectures on the white board, instilled in me the remarkable nature of these methods and the data I was collecting. It is do in large part to his mentoring, that my current research focus is centered on applying fMRI to explore the possible role of the cerebellar vermis in substance abuse and other psychiatric disorders.
In what follows, I will briefly outline the course of events, which has greatly influenced me and other colleagues to make the cerebellum a focus for studying substance abuse. A meeting with Dr. Julie Schweitzer at Emory University in 1998 originally sparked my interest in the vermis. While at Emory Dr. Schweitzer (working with Dr. Kilts) was then conducting PET imaging studies of adults with ADHD, retrospectively diagnosed as hyperactive during childhood. During this meeting, Dr. Schweitzer showed me data indicating that the cerebellar vermis was very responsive to the administration of stimulants. Investigating the literature (I only knew at that time that the cerebellar vermis could be damaged by ibogaine), I discovered that electrical stimulation of the vermis preclinically or clinically in cases of epilepsy or psychosis evoked profound changes in attention and forebrain dopamine release consistent with the psychological effects of stimulants such as methylphenidate. I then began an analysis of the cerebellar vermis in children enrolled in our study of methylphenidate dose response, which culminated in our published findings of dose- and rate-depenendent relationships between blood flow in the vermis and behavioral activity.
During the past seven years, working with Dr. Teicher and the Developmental Biopsychiatry group at McLean, I was also the primary investigator involved in the functional analysis of cerebral blood flow changes associated with early childhood sexual abuse. We had observed that blood flow in this region of the brain was abnormal in young adults who had experienced early childhood sexual abuse. These subjects also exhibited symptoms suggestive of limbic kindling, which were correlated individually with blood flow in the vermis and drug use was found to be greater within a larger group of young adults who also exhibited these symptoms. Because of these published findings I was invited to speak at a national meeting sponsored by CSAT/SAMHSA on trauma and substance abuse treatment following the 9/11 incident.
Ibogaine also appears to intensely activate the vermis according
to extensive pre-clinical and human studies (phase 1 clinical
trials were stopped at UM out of fear of cerebellar toxicity,
which, thus far, has not been observed). Rats given very high
doses of ibogaine develop lesions of the midline vermis, due to
excitory toxicity following the over-activation of climbing fibers.
Addicts experience several symptoms, consistent with over-activation
of the vermis, such as dizziness, transient ataxia, and auditory/visual
hallucinations. Taking into account these observations, and influential
epigenetic views of Zing-Yang Kuo I have formulated the hypothesis
that early trauma or lesions of the vermis may increase the risk
of developing substance use disorders. This hypothesis could be
presented at an invited lecture entitled "From Kuo to
the Cerebellar Vermis: Enhanced Risk for Substance Use Disorders
During Periadolescence as an Emergent Behavioral Neo-phenotype"
at the Society for Developmental Psychobiology Annual Meeting,
at the end of October, 2002 (if travel funds are avalible). In
brief, Kuo developed the concept of neo-phenotype to explain radically
aberrant deviations in species-typical behavior, induced by stressful
early experience. Recently, Dr. Giedd et al. observed that the
human cerebellum appears to be the most developmentally sensitive
brain region, a prime target for Kuo's stressful early experience.
In particular, regions of the vermis which mature postnatally
in humans contain high concentrations of the dopamine transporter
(DAT) in primates.
In collaboration with Dr. Marc Kaufman, I have localized,
using fMRI, the effects of MPH in normal adults to the same regions
of the vermis thought to be enriched in DAT. To further test
the association between addiction and the vermis, I have reanalyzed
fMRI data from a cue-induced cocaine-craving study previously
published by Maas et al. (1997). I discovered very a strong activation
of the anterior and posterior inferior regions of the vermis during
cue presentation, which was not present in controls. I presented
these findings in a talk entitled "Activation of lobule
VIII of the human cerebellar vermis by oral methylphenidate and
cue-induced cocaine craving" at the annual CPDD meeting
in Quebec this past June.
Research Funding Information:
Current Funding:
NIDA K01 DA016746-01A2 (Anderson, CM, P.I.) Children at Risk: High Field MRI of Stimulant Effects (09/01/05 – 08/29/08). Specific aims: IUndertake course work and practical training in the fundamentals of 1H- and 13C-MRS (Years 1-3). II:Observe treatment and develop research skills involving adolescents undergoing treatment for substance abuse at McLean Hospital (1st 6 months, Year 1). III:Extend and intensify didactic training in the background and methodology of nicotine and substance abuse research (Years 1-3)..V) Test the hypothesis, that glutamate concentrations [Glu] in the cerebellum decline during nicotine withdrawal and increase after nicotine-gum challenge, relative to nicotine-free comparison subjects, using 1H-MRS in nicotine dependent adolescents: and, VI) Quantify behavioral traits of activity, attention, and heart-rate change with nicotine gum as potential covariates of 1H-MRS. Aim VI: Use a subset of collected data as pilot data for an R01 to be submitted in year 2
Teaching/Invited Lectures:
Duke University Department of Psychology, Durham NC Graduate Assistant Instructor for Psy 103 "The Biological Basis of Behavior" Fall 1989, Spring 1990, Spring 1991.
Florida Atlantic University Department of Psychology, Boca Raton FL Graduate Assistant Instructor for Psy 3213 "Research Methods in Psychology" Fall 1994.
Invited Lecture on "The Emotions and REM Sleep" given at Florida Atlantic University, College of Liberal Arts, April, 3, 1995.
Invited Lecture on "The Connections Amoung Emotion, Arousal and Sleep Both at the Behavioral Level and the Physiological Level" given for Psychology 101 at the University of North Carolina at Asheville, July, 7, 1995.
Invited Lecture on "Maternal Deprivation Alters Spontaneous Patterns of Activity" in acceptance of the 1996 Dissertation Award, International Society for Developmental Psychobiology, Georgetown, Washington, DC.
Invited to the 1998 University of Arizona Consciousness Studies
Summer Institute on "Brain, Emotional Experience, and Culture."
at the Fetzer Institute in Kalamazoo, MI. July 28-Aug 1st.
"Maternal Deprivation Alters the Fractal Structure of Spontaneous Patterns of Behavior" given for the Department of Neurology, Emory University, Atlanta, GA., June 21st 1998.
"The Cerebellar Vermis, REM Sleep and Self Organized Criticality: A Tale of Tails and Timescales" given the Hobsen Lab, Harvard Medical School, January, 13rd, 1999.
"fMRI Measures of the Cerebelluar Vermis in Childhood ADHD" given at the APA Boston symposium on The Application of Neuroimaging Methods to Understanding Developmental Disorders, August 23rd, 1999.
"The Cerebellar Vermis and Psychopathology: Historical and Functional Imaging Perspectives" given at the Neuroscience Seminar McLean Hospital, December 21st 1999.
"The Cerebellar Vermis as the Cortex of the Protoself " given at the Affective Neuroscience Meeting, Playa del Carmen, Mexico, January 21st 2000.
"The Cerebellar Vermis and Psychopathology: Developmenatal, Historical and Functional Imaging Perspectives" given at Child Psychiatry Branch, NIMH Building 10, February 24th 2000.
"The Integrative Role of the Cerebellar Vermis in Cognition and Emotion" given at the 22th Annual Conference of the Cognitive Science Society, University of Pennsylvania, Philadelphia, PA., August 14th, 2000.
"A Role for the Cerebellum in the Neurobiology of ADHD" given at the Wenner-Gren and Karolinska Institute sponsored International Symposium on "Neurobiology of Attention Deficits and Hyperactivity Disorder", at the Wenner-Gren Center, Stockholm, Sweden, August 25th 2000.
"Functional Imaging of the Cerebellar Vermis in Children and Adults with ADHD" presented at the OPTAX Research Symposium, Burlington, MA. December 12th,2000.
"The Vermis of the Cerebellum: From Fetal REM Sleep to Cognitive and Emotional Intergration" presented at the International Conference on Pediatrics, University of New England, Biddeford, Maine, September 8th, 2001.
"Recent Developments in the Neurobiology of ADHD: From Anatomy to Functional Imaging" presented at the OPTAX Research Symposium, Burlington, MA. November 29th,2001 and the Department of Psychiatry, University of Florida, Gainesville, Fl. December 12th 2001.
"New Perspectives on the CerebellarVermis: From Fetal REM Sleep to Drug Addiction" Providence Sleep Research Interest Group at the sleep study center, E.P. Bradley Hospital, Brown Medical School December 18th 2001.
Publications:(top)
2. Kilts CD, Anderson CM. The simultaneous quantification of dopamine, norepinephrine and epinephrine in micropunched rat brain nuclei by on-line trace enrichment HPLC with electrochemical detection: distribution of catecholamines in the limbic system. Neurochemistry International. 1986 9:437-445.
5. Kilts CD, Anderson CM, Bissette G, Ely TD and Nemeroff
CB. Differential effect of
antipsychotic drugs on the neurotensin concentration of discrete
rat brain nuclei. Biochemical
Pharmcology. 1988, 37: 1547-1554.
6. Kilts CD, Anderson CM, Ely TD, Mailman RB. The biochemistry
and pharmacology of mesoamygdaloid dopamine neurons. New York
Academy of Science, 1988, 537: 173-187.
7. Selz KA, Mandell AJ, Anderson CM, Smotherman WP, Teicher MH. Distribution of local Mandelbrot-Hurst exponents: motor activity in fetal rats of cocainized mothers and manic depressives. Fractals. 1995, 3: 956-967.
*8. Anderson CM, Mandell AJ, Selz JA, Terry LM,Robinson SR, Wong CH, Robertson SS, Smotherman WP. The Development of Nuchal Atonia Associated With Active (REM) Sleep in Fetal Sheep: Presence of Recurrent Fractal Organization. Brain Research.,787(2):351-357,1998 Mar 23, also published on the WWW at (http://www.elsevier.nl/cas/tree/store/bres/sub/1998/787/2/19001.pdf). or Printable version available (270491 bytes).
11. Anderson, CM. From molecules to mindfulness: How vertically convergent fractal time fluctuations unify cognition and emotion. Consciousness and Emotion 2000, 1(2): 1-33.
14. Leonard SK, Petitto JM, Anderson CM, Mooney DH, Lachowicz
J, Schulz DW, Kilts CD, Mailman RB. D1 dopamine receptors in the
amygdala exhibit unique properties. New York Academy of Science,
2002, (in press).
Reviews and Symposia proceedings:(top)
1. Kilts CD, Anderson CM, Ely TD, Mailman RB. The biochemistry and pharmacology of mesoamygdaloid dopamine neurons. In: The Meso-corticolimbic Dopamine System, PW Kalivas and CB Nemeroff (eds). The New York Academy of Sciences, 1988, 173-187.
2. Anderson CM, Holroyd T, Bressler SL, Nakamura R, Selz KA, Mandell AJ. 1/f-Like spectra in cortical and subcortical brain structures: a possible marker of behavioral state-dependent self organization. In: Noise in Physical Systems and 1/f Fluctuations, Peter J. Handel and Alma L. Chung (Eds.), St. Louis, AIP Conference Proceedings 1993, 285: 737-740.
3. Anderson CM, Mandell AJ. Fractal Time and the Foundations of Consciousness: Vertical Convergence of 1/f Phenomena from Ion Channels to Behavioral States. in: Fractals of Brain, Fractals of Mind: In Search of a Secret Symmetry Bond: Advances in Consciousnes Research, 7, M. Stamenov & G. Globus (Series. Eds.) & E Mac Cormac & M Stamenov (Vol. Eds.), published by "John Benjamin" (Amsterdam & Philadelphia). 1996.
(Reviewed in Nonlinear Dynamics, Psychology, and the Life Sciences, 2(2):149-156. 1998)
4. Schweitzer JB, Anderson CM, Monique E. Attention deficit hyperactivity disorder: neuroimaging and behavioral/cognitive probes. In: Functional Neuroimaging In Child Psychiatry, Monique Ernst and Judith M. Rumsey (eds). Cambridge University Press, Cambridge, U.K. 2000, pp. 278-297.
5. Schmahmann JD, Anderson CM, Newton N, Ellis RD. The function of the cerebellum in cognition, affect and consciousness: Empirical support for the embodied mind. Consciousness and Emotion, 2(2):273-309, 2001.
6. Teicher MH, Feldman R, Polcari A, Anderson CM, Andersen SL, Webster DM, Naualta CP, Early adverse experience and the neurobiology of boderline personality disorder. In Women's Health and Psychiatry, Kimberly H. Pearson, Shamsah B. Sonawalla and Jerrold F. Rosenbaum (eds). Lippincott Williams & Wilkins, Philadelphia, U.S.A. 2002, pp. 9-26.
7. Teicher MH, Andersen SL, Polcari A, Anderson CM, Naualta CP. Developmental neurobiology of childhood stress and trauma. In: Recent Advances in the study of Biological Alterations in PTSD, The Psychiatric Clinics of North America. (R. Yehuda Vol. Ed.). 25:1-31, 2002.
8. Anderson CM. Cerebellar Vermal Activity and Attention
Deficit Hyperactivity Disorder: Novel Perspectives on Cognitive
and Emotional Coordination. In: Brain Conference-Manual: Internationaler
Kinesiologie Kongress, Institut für Angewandter Kinesiologie,
DE, (German version pp. 15-22), (English version pp. 23-36), 2002.
Articles:
1. Anderson CM. Ibogaine Therapy in Chemical Dependency and Posttraumatic Stress Disorder: A Hypothesis Involving the Fractal Nature of Fetal REM Sleep and Interhemispheric Reintegration. Multidisciplinary Association For Psychedelic Studies, 1998, VIII:1, pp 5-14 also published on the WWW at http://www.maps.org/news-letters/v08n1/08105and.html or local server (long version)
2. Teicher MH, Anderson CM, Andersen SL, Polcari A. Neurobiological correlates of childhood maltreatment. In The Intersection of Stress, Drug Abuse, And Development. A Program Book for the National Institute on Drug Abuse, January 19-20, 2000.
3. Anderson CM. The integrative role of the cerebellar vermis
in cognition and emotion. From the symposia "The Role of
the Cerebellum in Cognition and Affect" Proceedings of the
22nd Annual meeting of the Cognitive Science Society, Philadelphia,
Pennsylvania, USA, Lawrence Erlbaum Associates, Mahwah, NJ. 2000.
pp. 10-15.
Patents and Inventions:
Teicher MH, Anderson CM, Renshaw PF, Maas LC Method and use
of Steady-State fMRI Relaxometery for Diagnosis of Attention-Deficit/Hyperactivity
Disorder (ADHD and Prediction of Treatment Response) U.S. Patent
No. 6,400,978
Anderson CM, Lowen SB, Renshaw PF, Teicher MH. Method and Apparatus
for Detecting and Assessing Drug Response In Mental Disorders.
U.S. Patent Application No. 10/162,529.
Anderson CM, Lowen SB, Renshaw PF, Rohan M. Method and Apparatus
for Directly Measuring and Compensating for Subject Motion During
Scanning. U.S. Patent in progress.
Academic Writings:
Anderson CM, The Development of Habituation: Noradrenergic Modulation of Olfactory Orienting in Infant Rats. Unpublished Master Thesis; Duke University, 1991.
Anderson CM, Behavioral State-Dependent Self-Oganization and Critical Point Phenomena: A Working Hypothesis. Unpublished. 1992.
Online Abstracts and Posters:(top)
1994
Anderson CM, Mandell AJ, Terry LM, Smotherman WP, Robinson SR, Wong CH, Robertson SS, Nathanielsz PW. Fractal time in the REM sleep of fetal sheep: the Hurst exponent as a developmental measure of behavioral state organization.Society for Neuroscience Abstract 1994, 20:156.
1995
Anderson CM, Mandell AJ, Selz JA, Terry LM, Smotherman WO, Robinson SR, Wong CH, Robertson SS, Nathanielsz PW. The fractal time behavior of nuchal atonia episodes associated with REM sleep in fetal sheep. Developmental Psychobiology. 1995 28:179.
1996
Anderson CM, Mandell AJ, Selz KA, Terry LM. The fractal time behavior of episodes of inactivity in the nuchal EMG of neonatal rats: Confirmation of the fractal time behavior of nuchal atonia in fetal sheep. Developmental Psychobiology. 1996 29:279.
Anderson CM, Mandell AJ, Terry LM, Smotherman WP, Robinson SR, Wong CH, Robertson SS, Nathanielsz PW. Global measures of nuchal atonia patterns in fetal and neonatal mammals. In Sleep Research 1996; Volume 25: 82. (M.H. Chase, L.D. Rosenthal, C. O'Connor, Eds.) Brain Information Service/Brain Research Institute, UCLA, Los Angeles. (onlineversion:http://www.websciences.org/cgi-shl/dbml.exe?Action=Query&Template=/APSS/indiv.dbm&ID=19960096 ). or download.
Teicher MH, Glod CA, Ito Y, Anderson CM, Andersen SL, McGreenery CE. Hemispheric asymmetry of EEG and T2* relaxation time in seasonal affective disorder (SAD) pre and post-light therapy. Society for Light Therapy and Biological Rhythms, 1996, 8:9.
Glod CA, Teicher MH, McGreenery CE, Polcari A, Anderson CM, Holt RN, Duncsik BS, Andersen SL Gender differences in hyperactivity of elementary school children. American Academy of Child & Adolescent Psychiatry. 1996, 12
Teicher MH, Polcari A, Anderson CM, Andersen SL, Glod CA, English CD, Renshaw P. Methyphenidate effects on hyperactivity and fMRI in children with ADHD. American Academy of Child & Adolescent Psychiatry. 1996, 12
Anderson CM, Mandell AJ, Selz KA, Terry LM, Andersen SL, Teicher MH. Maternal deprivation alters a REM sleep associated behavior. Neurosci. Abstr. 1996, 22:687
Anderson CM, Mandell AJ, Selz KA, Terry LM, Andersen SL, Teicher MH. Maternal deprivation alters spontaneous patterns of behavior. Developmental Psychobiology 30(3):241. 1997
Anderson CM, Teicher MH, Mandell AJ, Selz JA, Terry LM, Smotherman WO, Robinson SR, Wong CH, Robertson SS, Nathanielsz PW. Fractals provide a global measure of spontaneous intermittent behavior in fetal and neonatal mammals and fidgeting in children with attention-deficit hyperactivity disorder (ADHD). Dynamical Neuroscience Meeting, Washington, DC 1996.
1997
1998(top)
Link to other DBRP posters relavant to child abuse
C.M. Anderson, A. M. Polcari, C. E. McGreenery, L.C. Maas, P.F. Renshaw, M.H. Teicher. Enduring effects of child abuse on cortical fMRI. 1998 Neurosc. Abstr (see below).
C.M. Anderson, M.H. Teicher, A. Polcari, S.L. Andersen, C.A. Glod, L Mass, P. Renshaw. Putamen hypoperfusion in attention-deficit/hyperactivity disorder (ADHD) revealed by steady-state fMRI relaxometry. International Basal Ganglia Society Meeting, Ocean Edge Resort, Brewster, MA. Oct 15-18th, 1998.
1999(top)
Anderson CM, Polcari AM, McGreenery CE, Maas L, Renshaw P, Teicher MH. Cerebellar Vermis Blood Flow: Associations with Psychiatric Symptoms in Child Abuse and ADHD Society for Neuroscience, 1999, 25: 1637.
Anderson CM, Polcari AM, McGreenery CE, Maas L, Renshaw P, Teicher MH. Methylphenidate Dose-Dependently Alters Blood Flow In The Vermis But Not Basal Ganglia Of ADHD Boys. SOBP, April 2000.
Anderson CM, Maas L, Renshaw P, Teicher MH. Non-Invasive T2-Relaxation Time Measures Correlate With Gadolinium-Based Cerebral Blood Volume Estimates In The Putamen And Cerebellar Vermis Of Young Adults. 2000, 26: 1730.
Anderson CM, Lowen SB, Kaufman MJ, Teicher MH, Rohan M, Renshaw P. Selective methylphenidate induced blood flow alterations in lobules III, VIII, and IX of an adult with ADHD. SOBP, May 2001, 49(8S), p.93S.
Anderson CM, Teicher MH, Polcari AM, Renshaw P. Functional imaging of stimulant effects in the cerebellar vermis of children with ADHD: Implications of behavioral phenotyping. Drug and Alchohol Dependence, 63: supplement 1, p. S7.
Anderson CM, Teicher MH, Polcari AM, Renshaw P. Potential role of the cerebellar vermis in enhanced risk for substance abuse among adults sexually abused as children. Neurosc. Abstr. 2001, 27: 222.
Anderson CM , MM Silveri, R.Cowan, LC Maas, BK Madras, SE Lukas, PF Renshaw, MJ. Kaufman. Activation of lobule VIII of the human cerebellar vermis by oral methylphenidate and cue-induced cocaine craving. Drug and Alchohol Dependence 66: supplement 1, p. S6, 2002.
S.B. Lowen, B. de B. Frederick, M. Rohan, C.M. Anderson, L.C.
Maas, III, and P.F. Renshaw, Objective motion detection and correction
in time series fMRI experiments conducted on cocaine-dependent
subjects. Drug and Alcohol Dependence 66: supplement 1, pp. S106-107,
2002.
.
*Printable PDF files.
1998-Press Articles: (top)
Dreaming Linked to Brain Development.....By William J. Cromie....Harvard Gazette (June 3, 1998)
Harvard Gazette Article and My Corrections
20/20 -Goggle Thearpy: Can Taped Goggels Heal Emotional Disorders? (10-21-98)
Career Accomplishments (1996-1998)
-1996
May-June
Presented: Global Measures Of Nuchal Atonia Patterns In Fetal And Neonatal Mammals at APSS Washington, D.C.
*Invited Lecture given for Allan Hobson's Lab meeting.
*Invited Presentation: Fractals Provide A Global Measure Of Spontaneous Intermittent Behavior In Fetal And Neonatal Mammals And Fidgiting In Children With Attention-Deficit Hyperactivity Disorder (ADHD) at the Gordon Research Conferences N.H.
August
*Invited presentation: Hurst Analysis of Spontanoues Behaviors in Fetal and Neonatal Mammals and Fidgeting in Children with Attention Deficit Activity Disorder (ADHD). At the Bloomingdale Meeting in White Planes, NY August 1996
November
*Dissertation Award & Invited Lecture on "Maternal Deprivation Alters Spontaneous Patterns of Activity" in acceptance of the 1996, International Society for Developmental Psychobiology, Georgetown, Washington, DC.
-1997
April
Presented: Objective Actigraphy Of ADHD: Correlation With Optical Tracking at Harvard Annual Psychiatry Day, 4/16
September
Interviewed for New Scientist, Aug 16 issue on Fractal Time and the Brain.
November
Presented the following at International Society for Developmental Psychobiology and Socity for Neuroscience in New Orleans:
Functional asymmetry of the temporal lobes in young adults verbally and sexually abused as children using fMRI. Developmental Psychobiology, 1997.
Prevalence, distribution, and gender bias in attention and hyperactivity in school aged children. Neurosci. Abstr. 1997, 23: 1997.
Hemispheric asymmetry of EEG and fMRI in seasonal affective disorder (SAD) pre and post-light therapy. Neurosci. Abstr. 1997, 23: 561.
Mult-time-scale analysis of fluctuations in BOLD fMRI. Neurosci. Abstr. 1997, 23: 1575.
-1998
March
Press release for paper: The Development of Nuchal Atonia Associated With Active (REM) Sleep in Fetal Sheep: Presence of Recurrent Fractal Organization. Brain Research.,787(2):351-357, 1998, also published on the WWW at (http://www.elsevier.com/locate/bres).
Picked up by Harvard Gazette (June 3, 1998).
Belmount Post (June 4, 1998).
Brown University Child and Adolescent Behavioral Letter (Sept. 1998).
April
Presented fMRI Measures Of Hemispheric Asymmetry In Young Adults Verbally Or Sexually
Abused As Children: Implications For Dissociated States Of Consciousness. at Tuson III, Toward a Science of Consciouness, April 26th-May 2, 1998.
June
Awarded $20,000 in a grant from University of Arizona for "Mind Wandering and the Amygdala."
July
Invited to the 1998 University of Arizona Consciousness Studies Summer Institute on "Brain, Emotional Experience, and Culture." at the Fetzer Institute in Kalamazoo, MI. July 28-Aug 1st.
September
Interviewed along with Dr. Fredric Schiffer for 20/20 in reference to EEG and fMRI studies reported in Dr. Schiffer's book "Of Two Minds."